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  4. T. 72, № 5, 2022

Журнал высшей нервной деятельности им. И.П. Павлова, 2022, T. 72, № 5, стр. 678-689

Транскраниальная электростимуляция постоянным током модулирует компонент негативности результата действия в монетарной игре

А. А. Горин 1, 2, *, В. А. Ключников 1, И. И. Дутов 1, В. В. Моисеева 1, В. А. Ключарев 1, А. Н. Шестакова 1

1 Институт когнитивных нейронаук, Национальный исследовательский университет Высшая школа экономики
Москва, Россия

2 Центр нейробиологии и нейрореабилитации имени В. Зельмана, Сколковский институт науки и технологий
Москва, Россия

* E-mail: gorinspbu@gmail.com

Поступила в редакцию 15.03.2022
После доработки 10.05.2022
Принята к публикации 27.06.2022

Аннотация

Настоящее исследование было направлено на изучение нейрофизиологических эффектов транскраниальной стимуляции постоянным электрическим током (tDCS) в отношении компонента вызванных потенциалов, называемого “негативность результата действия” (feedback-related negativity, FRN). Испытуемые выполняли задачу на отложенное денежное подкрепление, во время которой пытались избежать денежных потерь различной величины. Мы сравнили амплитуду FRN в ответ на информацию о денежной потере в контрольной группе с группой, получавшей катодную стимуляцию вентромедиальной префронтальной коры. Основываясь на имеющихся в литературе данных, мы предположили, что катодная tDCS будет подавлять амплитуду компонента FRN. Вопреки нашей гипотезе, величина компонента в группе стимуляции была значимо выше, чем в контрольной группе. Данные результаты могут служить как дополнительным свидетельством усиливающего действия катодной tDCS, так и привести к предположению о том, что нейросети, участвующие в генерации сигнала при обработке денежной потери, отличаются от таковых при игре, не связанной с денежным вознаграждением.

Ключевые слова: ЭЭГ, вызванные потенциалы, ТЭС

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