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Физиология растений, 2023, T. 70, № 7, стр. 715-735

Фуранокумарины зонтичных: история исследования, разнообразие, генетические основы синтеза, физиологическая роль в растении и применение в медицине

В. Ю. Штратникова *

Федеральное государственное бюджетное образовательное учреждение высшего образования “Московский государственный университет имени М. В. Ломоносова” Научно-исследовательский институт физико-химической биологии им. А. Н. Белозерского
Москва, Россия

* E-mail: vtosha@yandex.ru

Поступила в редакцию 06.09.2023
После доработки 05.10.2023
Принята к публикации 15.10.2023

Аннотация

Обзор посвящен фуранокумаринам – классу веществ, представляющих собой совмещение пиронового, бензольного и фуранового колец, обладающих системой сопряженных двойных связей (которая в ряде случаев может нарушаться). Эта группа соединений широко изучается в настоящее время благодаря своим фототоксическим и лекарственным свойствам. В работе рассмотрены фуранокумарины естественного происхождения, выявленные в семействе Umbelliferae (Зонтичные), или Apiaceae (Сельдерейные), структурировано их многообразие, описана история исследования, известные к настоящему времени этапы их биосинтеза, а также некоторые примеры их биологической активности в растении, в культуре клеток и при медицинском использовании.

Ключевые слова: биологическая активность, биосинтетические пути, фуранокумарины, Apiaceae, Umbelliferae

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